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After another MinElute purification, the product was quantified using the Agilent 2100 Bioanalyzer DNA 1000 chip. & Steinrcken, M. Parental relatedness through time revealed by runs of homozygosity in ancient DNA. Hi, my name is Tina and I'm a data scientist at a FAANG company. of Leiden, 2000). In addition, our phylogeographic analysis points to northeastern Italy as the possible entry point of the Epigravettian-associated gene pool in the Italian peninsula. PACEA co-authors of this research benefited from the scientific framework of the University of Bordeauxs IdEx Investments for the Future programme/GPR Human Past. 7, eabd6535 (2021). "Ice Age survivors." 864358 (to K.M. Green, R. E. et al. (grey) of the f4 values estimated from 5cM-block jackknife analysis. A software engineer who now works as a content creator full-time, Mayuko Inoue runs a YouTube channel dedicated to software engineering, working in the tech industry, and life in general. A user manual including an installation guide is available at https://haproh.readthedocs.io/en/latest/hapROH_with_contamination.html. Mid and Late Upper Palaeolithic in the Adriatic Basin: chronology, transitions and human adaptations to a changing landscape. The version used for this work is archived at https://edmond.mpdl.mpg.de/dataset.xhtml?persistentId=doi:10.17617/3.Y1KJMF. Tina Zhang - Brand Specialist - Dymind Biotechnology | ZoomInfo The Villabruna ancestry later appeared in central Europe and it is thought to have largely replaced groups related to the GoyetQ2ancestry4. Extended Data Fig. Interactions between people from central and eastern Europe can only be detected again from 8,000 years ago. Tina Llorca CPA, CWP, CEPP, CIS, MDRT'S Post - in.linkedin.com Overall, the literature suggests that Chinese Canadian students demonstrate high levels of achievement and that this academic success is associated with factors such as stronger feelings of ethnic identity, better English language skills in the family, Chinese . The developed methyl gallate/cellulose acetate membrane exhibited PWF of 56.28 2.10 L m -2 h 1 and rejection rates of 99.14 0.03 % against oil emulsion. CONTACT US Contact us. 2023 365 Data Science. As previously hinted37, we find a large frequency variation in alleles related to skin and eye pigmentation among post-LGM hunter-gatherer groups. Become an in-demand #DataScience professional TODAY with the 365 Data Science Program -> https://365datascience.com, analyzing similar products to compare how they performed, data visualizations with SQL and Python or R. A dashed line of 50 cM total ROH is drawn in each panel to help comparison between panels with different y-axis scales. Her advice appears very solid, and she knows about the difficulties and barriers students are faced often when preparing for job interviews. Tina Huang Popularity . Tina Huang | Propel | Build Something Together Here is a sampling of five herbs that have demonstrated potential immune support benefits: 1. Tina Huang, a former engineer at Apple, Google, and Twitter, explains why she started API management startup Transposit. 2011. For individual heterozygosity calculation, we also called pseudo-diploid genotypes from each library, using pileupCaller 1.4.0.3 under random diploid calling mode and the same strategy for different types of libraries as pseudo-haploid genotype calling. Ideally, we also want lots of data because this will give us more confidence in our results. Epoxy Flooring UAE; Floor Coating UAE; Self Leveling Floor Coating; Wood Finishes and Coating; Functional Coatings. In particular, the 13ka Pradis 1 individual from northeastern Italy represents the most basal lineage compared to all other Epigravettian-associated individuals, including the older Tagliente 2 and Villabruna genomes from northern Italy (group 1). Google Scholar. This is one of the things that make us stand out from other platforms which usually consider mathematics and statistics a prerequisite. To determine the Y-chromosome haplogroups of male individuals, we genotyped the Y-chromosome reads using a Y-SNP list (v.15.73) from the International Society of Genetic Genealogy (ISOGG) dataset, ignoring C-to-T and G-to-A transitions on the forward and reverse reads, respectively. Tina Huang is a statistician who focuses on the statistical modeling and analysis of big data. Extended Data Fig. Subsequently, I worked in . Li, H. et al. I came across her YouTube through Ken Jee. Klaric, L., Goutas, N., Laccarire, J. Tina Huang - Test and Validation Engineer - LinkedIn Data science is a lot like cooking. Ancient admixture in human history. My name is Tina and I'm a data scientist at a FAANG company. USA 117, 1279112798 (2020). In the video above, she explains the two major components of big data: data warehousing and data science. In this admixture graph, the lineage related to Zlat k splits more basally than the Bacho Kiro IUP group, who contributes to Tianyuan, UstIshim and Goyet Q116-1 (indicated with red lines), but not to the Sunghir group. View Tina Huang's profile on LinkedIn, the world's largest professional community. I help students become independent data scientists who are not just good at data analysis, but are also able to think about their own learning and the world around them. To bind DNA, silica columns for high volumes (High Pure Viral Nucleic Acid Large Volume Kit (Roche)) were used. Follow. Use the Previous and Next buttons to navigate the slides or the slide controller buttons at the end to navigate through each slide. 1c) and a west Eurasian principal component analysis (PCA) (Extended Data Fig. At this startup dedicated to b2b marketing, we, the data team formed by 2 people, are organizing all the data from zero and looking for their real value. We give some of our best tips to improve them and hopefully help you all land a data science interview. The oldest genomes carrying ancestries that derive primarily from the lineage leading to present-day Europeans are Kostenki 14 (from 37ka, with uncertain archaeological association from western Russia), Goyet Q116-1 (35ka, Aurignacian-associated from Belgium) and Bacho Kiro 1653 (35ka, probably Aurignacian-associated from Bulgaria)2,4,8. Quat. Edgar, R. C. MUSCLE: multiple sequence alignment with high accuracy and high throughput. From at least 14,000 years ago, an ancestry related to this culture spread from the south across the rest of Europe, largely replacing the Magdalenian-associated gene pool. Villalba-Mouco, V. et al. The suspension was then centrifuged and transferred into a binding buffer as previously described56. AMAZING COURSE! Instead, in southern Europe, a distinct hunter-gatherer genetic profile was found as early as 17ka in individuals associated with the Epigravettian culture15 (2412ka, from the Italian peninsula to the southeastern European Plain across the Balkans). Her YouTube channel offers tips on productivity hacks, resume evaluations, data science employment, and more. Conversely, individuals in the Sidelkino cluster are genetically closer to AG3 than Tutkaul 1. Tina Huang Data Scientist. The latter was created as a support network for women in the industry to discuss, share, and learn from each other.. Article My main tasks: Modeling and developing the data structures and processes to optimize the loads of information, discovering insights and creating and maintaining reports. Commun. 1 MtDNA and Y-chromosome phylogenies. 2. I am Tina Huang, PhD, a data scientist, and the director of the Data Science Learning Center at the University of Arizona. . Note added in proof:A companion paper51describes genome-wide data of a 23,000-year-old Solutrean-associated individual from southern Iberia that extend the evidence of genetic continuity across the LGM in southwestern Europe. Protoc. 771234-PALEoRIDER (to W.H. Notably, this genetic distinction coincides with dissimilarities in mortuary practice among genetically analysed Gravettian-associated individuals from different parts of Europe. As the coverage for most ancient samples was not sufficient for diploid genotype calling, we counted the reads covering selected phenotypic SNPs on reference or alternative alleles and computed the group-based allele frequencies following a maximum likelihood approach described in Mathieson et al.37. 3). 44, W58W63 (2016). In our case, we had data about people who had fallen off the internet, and we wanted to predict the probability that they would fall off at a certain time. Interviewed Taiwanese designers and analyzed the interview data. The increasing level of admixture between distinct hunter-gatherer populations from around 8ka onwards indicates an intensified mobility of those forager groups. "It is possible that the migration of early farmers into Europe triggered the retreat of hunter-gatherer populations to the northern edge of Europe. Branch labels show unique drift lengths; black dots refer to individuals with newly generated data and white dots refer topreviously published genomes;the position of each node does not imply the location where the split took place. The Italian peninsula was previously considered to be another climatic refugium for humans during the LGM. National Science Council feb. 2009 - feb. 2009 1 maand. Tina Llorca CPA, CWP, CEPP, CIS, MDRT Expand search. The Sidelkino ancestry also emerged around 14ka with its first direct evidence in eastern Europe43 dated to 13ka. Madrid, Madrid, Spain. Ice Age survivors. The genetic affinity to the Villabruna ancestry is present in El Mirn and in Magdalenian-associated individuals from western and central Europe. This free online conference is featuring panel discussions from Tina_Huang_Resume_i.pdf - Tina Huang hellotinah@gmail.com C. Posth and H.Y. Lazaridis, I. et al. . K.H. For ds_halfUDG libraries, we called genotypes on all targeted sites from 2bp-masked bam files; for ds_nonUDG libraries, we called genotypes on transversion sites only; for ss_nonUDG libraries, we called genotypes with single-strand mode, which ignores forward reads at C/T polymorphisms and reverse reads at G/A polymorphisms. S. Shnaider received support from theRussian Science Foundation (no. Modern humans have populated Europe for more than 45,000 years1,2. Thats exactly why choosing the right feature to build is so important! Bilateral trade between China and Russia in 2022 rose 34.3% year-on-year to a record high of 1.28 trillion yuan ($190 billion) in yuan-denominated terms, Chinese customs data showed in early January. First, I like it because of how powerful (almost magical) it is in driving decisions. Biol. OUR UNIVERSITY Our University . After the LGM, the Epigravettian culture was widespread in southern andsoutheastern Europe. Quat. The ethane yield of 35.4 mol/h with a high C 2 . E.A. Rep. 10, 21931 (2020). In her journey of eventually. TV Actress. Hi! Shes the author of the popular Data Science: The Complete Guide and the creator of the popular Data Science Cookbook. She was also one of the founders of the Stanford Data Science Society. Bioinformatics 38, 37683777 (2022). eLife 11, e77625 (2022). Curr. Hunter-gatherers across the great Adriatic-Po region during the Last Glacial Maximum: environmental and cultural dynamics. Tina Huang | Data Scientist | Udemy Jnsson, H., Ginolhac, A., Schubert, M., Johnson, P. L. F. & Orlando, L. MapDamage2.0: fast approximate Bayesian estimates of ancient DNA damage parameters. analyzing similar products to compare how they performed, data visualizations with SQL and Python or R, Unimex NetworkPrice Analysis 2021 UMX Token Price Forecast 2021 Umx Token Price Prediction 2021, NKN Token Price Analysis 2021 Nkn Token Price Forecast 2021 nkn Token Price Prediction 2021, CRED Price Analysis 2021 LBA Token Price Forecast 2021 Lba Token Price Prediction 2021, Pearl Price Analysis 2021 PEARL Token Price Forecast 2021 pearl Token Price Prediction 2021, JackPool Price Analysis 2021 JFI Token Price Forecast 2021 Jfi Token Price Prediction 2021, CyberFi Price Analysis 2021 CFI Token Price Forecast 2021 CFI Price Prediction 2021, UNISTAKE Price Analysis 2021 UniStake Token Price Forecast 2021 Unistake Price Prediction 2021, OctoFi Token Price Analysis 2021 OCTO Token Price Forecast 2021 Octo Token Price Prediction 2021, Hedera Hashgraph Price Analysis 2021 HBAR Token Price Forecast 2021 -Hbar Price Prediction 2021. You have to deal with large datasets; however, you have to do your work in a way that makes sense to your team. 21, 199 (2020). Genome Biol. ISSN 0028-0836 (print). Dismiss. Rohland, N., Harney, E., Mallick, S., Nordenfelt, S. & Reich, D. Partial uracilDNAglycosylase treatment for screening of ancient DNA. The genomic history of southeastern Europe. The previous inhabitants may have migrated to the north as their habitat, the 'mammoth' steppe, dwindled," says Johannes Krause, the study's senior author. Dolukhanov, P. in Cultural Transformations and Interactions in Eastern Europe (eds Chapman, J. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate. Peltzer, A. et al. Living up to Expectations: The Strengths and Challenges Experienced by In product development, 80% of the success of a product is determined by 20% of its features. Int. Ice Age survivors. Biol. Article The Kostenki genetic signature (related to the Kostenki 14 genome, and hereafter referred to as the Kostenkicluster or ancestry) contributed to the later Vstonice genetic cluster(hereafter,Vstonice cluster or ancestry), named after the Doln Vstonice site in Czechia4. Citations 52. 2b). J. Archaeol. A similar pattern is observed through the analysis of ROH segments (Extended Data Fig. The similarity between Goyet Q116-1 and Goyet Q376-3 and the Fournol cluster is also observed at the mtDNA level, with both groups including individuals who carried mtDNA haplogroup M, which has not been found in European individuals from after the LGM24 (Extended Data Figs. This course will help you build a deliberate strategy when participating in a data scientist job interview involving SQL. PubMed Dabney, J. et al. 27, 576582 (2017). Look here to get updated on my recent favourite books, animes, filming equipment and more! Along with pushing for more accessibility, she also creates content around working in the tech industry, the challenges that come with it, and career advice. In addition to her rich experience, including bioinformatics cancer research at OICR, Tina is a . We then attempted to model 250 published and newly reported hunter-gatherers dated to 145ka using qpAdm as a mixture of Oberkassel, Sidelkino, GoyetQ2 ancestries, and an ancestry maximized in Anatolian Neolithic farmers (ANF), as a considerable portion of the sequenced hunter-gatherer genomes date after around 8ka, when ANF ancestry started spreading across Europe. In general, the whole point of data warehousing is to get the data from your source to your target. Lifetime access to all course materials and updates. Archaeological background, method descriptions and discussions additional to the main text, including sections 113, Figs. Tina Huang is a recent graduate of Stanford. All remains were sampled with the approval of the institutions responsible for the analysis of archaeological material. Extended Data Fig. Happy International Womens Day! Genome Biol. In the box plot the centre line is the median, box bounds delineate the interquartile range and whiskers extend to maximum and minimum values, excluding outliers. Check out Bootcamps Yes or nah? 2023 in science - Wikipedia K.N., V.V.-M., R.R., T. Ferraz, R.T., D.G.D., M.L., A. Modi, S. Vai, T. Saupe, C.L.S., G. Catalano, L. Pagani, D.C. and E.A. A phylogeographic reconstruction of different lineages carrying this ancestry further suggests its entry point into northeastern Italy from the Balkans followed by a north-to-south expansion into the Italian peninsula alongside a population decline through sequential bottlenecks. Tina started her YouTube channel in 2020. Tina Huang. 8 Effective tina huang data science Elevator Pitches Our knowledge of the genetic relatedness and structure of ancient hunter-gatherers is however limited, owing to the scarceness . Bortolini, E. et al. "At that time, hunter-gatherers with distinct ancestries and appearances started to mix with each other. Follow a proven methodology, discover how to avoid common mistakes and impress employers as the best person for the job. 272273, 354361 (2012). USA 111, 22292234 (2014). of estimates from 5-cM-block jackknife analysis. Proc. What is Marimekko Chart in Data Visualization? a, MDS plot of pre-LGM individuals. Test cases development, automated test tool design, and validation testing for Alaris' first attachable/detachable infusion pump, which is . van de Loosdrecht, M. et al. 27 and 28 and Supplementary Data 3.G. Genome Biol. This derived ancestrythe Fournol clustersurvived during the LGM in Solutrean-associated individuals, possibly within the Franco-Cantabrian climatic refugium25, leading to later populations associated with the Magdalenian culture (GoyetQ2 cluster and El Mirn). 2a). Moreover, the almost complete genetic replacement of the Magdalenian-associated gene pool raises the hypothesis that parts of Europe were differentially populated during the abrupt climatic variation starting around 14.7ka with the BllingAllerd warming period, creating areas where southern European populations could expand. The observation that post-14ka individuals from western and central Europe andalso from Britain41 carry a homogeneous genetic makeup instead of displaying repeated local admixtures with GoyetQ2 ancestry implies that the Oberkassel-ancestry profile was already largely formed before its dispersal. use of cookies The admixture graph shows that the Bacho Kiro IUP group (n=3) shares ancestry with multiple early modern human lineages2 (Supplementary Information, section7), and that the more than 45,000-year-old Zlat k genome1 is the most deeply divergent non-African lineage sequenced to date (Extended Data Fig. The effective population sizes (Ne) were then estimated using a maximum likelihood method, after filtering individuals with a signal of close-kin inbreeding (individuals with at least 50 cM of their genome in ROH spanning >20 cM) (Supplementary Information, section9). Ive always liked the idea of using data to make predictions. Our analyses demonstrate that the Fournol cluster is a better source for Magdalenian-associated genomes than Goyet Q116-1. Further palaeogenomic studies on Upper Palaeolithic individuals from the Balkans will be essential for understanding whether southeastern Europe represents the source of the Villabruna ancestry and a climatic refugium for human populations during the LGM. However, the genetic profile of contemporaneous Gravettian-associated individuals from western Europe remains unknown, as is their contribution to populations after the LGM. Tina Huang. Low latency, reasonably low communication overhead and ability to support real time applications are the reasons for . Tina Huang - Senior Tax Analyst - Lion | LinkedIn The course is well structured and just what one needs before preparing for a data science interview with focus on SQL. Evol. In addition to this general data science content, Tina teaches SQL . Anti Slip Coating UAE 4a). Thats it for today. Genomic insights into the origin of farming in the ancient Near East. Seguin-Orlando, A. et al. A deft hand at turning dense and complicated topics into informative and entertaining videos, theres a ton to learn from every single video. Join a growing community of 11K+ to find accountability partners, take part in productivity sprints, and join discord only events! Develped strategies for promoting G-Mark to Taiwan. On the basis of the genetic variation of present-day Europeans, this could imply phenotypic differences between post-14ka hunter-gatherer populations across Europe, with individuals in the Oberkassel cluster possibly exhibiting darker skin and lighter eyes, and individuals in the Sidelkino cluster possibly lighter skin and darker eye colour. The key areas to focus on when getting started in data science [6:01] Tina's five steps to consistently doing anything [11:55] Tina's day-to-day life as a data scientist at one of the world's largest tech companies [20:02] How Tina's computer science background helps her work [26:20] Traditional banking culture vs big tech [32:12] Contrary to the proposal in Fu et al.4 but in agreement with Petr et al.17, we do not observe a substantial decrease of Neanderthal ancestry in most European hunter-gatherers through time (Supplementary Information, section6 and Supplementary Figs. Genome of Petera Muierii skull shows high diversity and low mutational load in pre-glacial Europe. However, its formation, diffusion and interaction with contemporaneous hunter-gatherers from eastern Europe and their interplay with later expansions of Neolithic farmers from southeastern Europe are not well characterized. Tina Huang is a Data Scientist at a FAANG (Facebook, Amazon Apple, Netflix, Google) company. Nat. https://doi.org/10.1038/s41586-023-05726-0, DOI: https://doi.org/10.1038/s41586-023-05726-0. www.sciencedaily.com/releases/2023/03/230301120846.htm (accessed March 4, 2023). Considering a freshwater reservoir signal in the upper Volga region making radiocarbon dates on human remains appear up to about 500 years older than their true age44, there could be an interval of more than 1,000 years between the first evidence of admixture in central European hunter-gatherers with Sidelkino ancestry and eastern European hunter-gatherers with Oberkassel ancestry. How to Rock at Data Science with Tina Huang, Older: Daily Habit #8: Math or Computer Science Exercise . The population history of northeastern Siberia since the Pleistocene. Gonzlez-Fortes, G. et al. Tina Huang, a data scientist currently working at a FAANG (Facebook, Amazon, Apple, Netflix, and Google Alphabet) company. The science policy "Framework for Federal Scientific Integrity Policy and Practice" issued by the White House Office of Science and Technology Policy a day later is criticized as a "gag order" on scientists by PEER in an open letter (30 Jan). Patterson, N. et al. Libraries showing a mitochondrial or nuclear contamination rate over 10% were considered substantially contaminated whereas those between 5 and 10% were considered marginally contaminated and were treated differently (details are provided in Supplementary Information, section3). H. Rougier received support from the College of Social and Behavioral Sciences of CSUN and the CSUN Competition for RSCA Awards. de Investigacin en Arqueologa y Patrimonio Histrico, University of Alicante, Sant Vicent del Raspeig, Alicante, Spain, Javier Fernndez-Lpez de Pablo&Magdalena Gmez-Puche, Amsterdam Centre of Ancient Studies and Archaeology, University of Amsterdam, Amsterdam, The Netherlands, Department of Anatomy, Histology and Anthropology, Faculty of Medicine, Vilnius University, Vilnius, Lithuania, Service Rgional de lArchologie de Bourgogne-Franche-Comt, Besanon Cedex, France, Laboratoire de Chrono-Environnement, UMR 6249 du CNRS, UFR des Sciences et Techniques, Besanon Cedex, France, Institute of Pre- and Protohistory, University of Tbingen, Tbingen, Germany, Department of Archeological Sciences, Thuringian State Office for Monuments Preservation and Archeology, Weimar, Germany, University of Bucharest, Faculty of Geology and Geophysics, Department of Geology, Bucharest, Romania, Institute for Advanced Studies in Levant Culture and Civilization, Bucharest, Romania, German Archaeological Institute, Berlin, Germany, Brandenburg Authorities for Heritage Management and Archaeological State Museum, Zossen, Germany, Institute for Pre- and Protohistory, Kiel University, Kiel, Germany, Institute of Archeology at Brno, Czech Academy of Sciences, Centre for Palaeolithic and Paleoanthropology, Brno, Czechia, Institute of Archaeology, Academy of Sciences of the Republic of Tatarstan, Kazan, Russia, Samara State University of Social Sciences and Education, Samara, Russia, Early Prehistory and Quaternary Ecology, Department of Geosciences, University of Tbingen, Tbingen, Germany, Paleoanthropology, Institute for Archaeological Sciences, Department of Geosciences, University of Tbingen, Tbingen, Germany, DFG Centre for Advanced Studies Words, Bones, Genes, Tools, University of Tbingen, Tbingen, Germany, Royal Belgian Institute of Natural Sciences, Brussels, Belgium, Institute of Archaeology Russian, Academy of Sciences, Moscow, Russia, School of Archaeology, University of Oxford, Oxford, UK, Peter the Great Museum of Anthropology and Ethnography (Kunstkamera), Russian Academy of Sciences, Saint Petersburg, Russia, Department of Cultures, University of Helsinki, Helsinki, Finland, Seminar for Pre- and Protohistory, Gttingen University, Gttingen, Germany, Lower Saxony State Service for Cultural Heritage, Hannover, Germany, Department of Human Genetics, Leiden University Medical Center, Leiden, The Netherlands, You can also search for this author in