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5 0 obj Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. Brand-name medications usually cost more than generics. Do not double the dose to catch up. Following an LSD trip, users may experience a sort of 'comedown.'. The oral form of the drug, called sucroferric oxyhydroxide and used . Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. WARNINGS/CAUTIONS: Serious hypersensitivity reactions, including anaphylactic-type reactions (itching, hives, swelling, wheezing, difficulty breathing, fainting and/or other allergy symptoms), some of which have been life threatening and fatal, have happened in patients receiving Venofer. 1 0 obj Common and Rare Side Effects for Venofer Vial - WebMD Serious side effects should be reported to a physician and/or PharmD for medical advice. Allergic reactions typically occur the first time your body is exposed to a drug. Venofer (iron sucrose injection, USP) Rx Only DESCRIPTION Venofer (iron sucrose injection, USP) is a brown, sterile, aqueous, complex of polynuclear iron (III)-hydroxide in sucrose for intravenous use. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. However, some people can experienceside effectsfor much longer - days, months, or indefinitely. Drug interactions: DayQuil can interact with other medications, including prescription drugs, over-the-counter medications, and herbal supplements. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. If you have questions about the blood tests youll need to have done to monitor your anemia, talk with your doctor. Pain, swelling, or redness at the injection site may occur. Venofer Side Effects. Get emergency medical help if you have signs of an allergic reaction to Venofer: hives, rash, itching; feeling light-headed; difficulty breathing; swelling of your face, lips, tongue, or throat. How Long Do Side Effects Last | Education Center - Sequencing experience severe side effects, please seek medical attention right away and notify the ordering physician. Ask your doctor or healthcare provider if Venofer is the right choice for you. This test measures the amount of hemoglobin in your blood. Headache. Precautions. To learn about other mild side effects, talk with your doctor or pharmacist, or see Injectafers package insert. People with IDA have low blood levels of hemoglobin. After getting one treatment course of Injectafer, you typically wont need another dose of the drug again unless your anemia comes back. Here's some detail on certain side effects this drug may cause. Why is the range so wide? In clinical studies, diarrhea was reported in less than 1% of people taking Injectafer. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. This is not a complete list of side effects and others may occur. But in some people, Injectafer can cause symptoms of hypophosphatemia to occur. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. signs of inflammation in the lining of your stomach --pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. Common MRI side effects include dizziness, anxiety, headache, nausea, hearing loud noises, and feeling chilled or hot in the MRI scanner. If you think there has been an overdose, call your poison control center or get medical care right away. I was surprised too but the Dr said it definitely sounds like a reaction. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. . Once you have waited for 30 minutes after the injection, you may go home, providing you are feeling well. Keep all medications away from children and pets. They can recommend if this is safe for you to do. Data on file, American Regent, Inc. 1. Mental healthdisorders like depression may requireantidepressantsto treat. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. Storage Condition Store in a cool and dry place protected from light. Call your doctor for medical advice about side effects. It will take about three weeks to feel the effects but your fatigue will disappear and you will feel like a new person. So the goal of anemia treatment is to increase your hemoglobin level back to a value thats within a normal range. Venofer (iron sucrose) is given by injection into a vein as directed by your doctor. I'm contemplating getting infusions again but I've always been a bit worried that they could cause issues in the long run. Throw away unused or expired drugs. Otherwise, call a poison control center right away. Red Tide in Florida: What You Need to Know | OutCoast.com It is usually given slowly over 2 to 5 minutes or as directed by your doctor. But for most people whove developed hypophosphatemia with Injectafer, the condition resolved within 3 months. Both of theseside effectscould worsen depression and lead tolife-threateningconsequences. Venofer - Iron sucrose uses, dose and side effects - zeepedia.com For more information about Injectafers approved uses, see the section Injectafer uses below. Tell your doctor if you are pregnant or plan to become pregnant. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Severeside effectscan lead to injury or death -drowsinesscan cause a car accident or injury when operating heavymachinery. If you notice any changes to your normal blood pressure, call your doctor right away. fluid retention, especially in your arms, legs, or feet, people who took Feraheme had their hemoglobin level increase, on average, by 1.38 grams per deciliter (g/dL), people who took ferric carboxymaltose had their hemoglobin level increase, on average, by 1.63 g/dL, having strange cravings to eat items that arent food, such as ice, people who took Injectafer had their hemoglobin level increase, on average, by 1.6 grams per deciliter (g/dL), people who kept taking iron by mouth had their hemoglobin level increase, on average, by 0.8 g/dL, people who took Injectafer had their hemoglobin level increase, on average, by 2.9 g/dL, people who took the other intravenous iron product had their hemoglobin level increase, on average, by 2.2 g/dL, people who took Injectafer had their hemoglobin level increase by an average of 1.1 g/dL, people who took Venofer had their hemoglobin level increase by an average of 0.9 g/dL, cannot tolerate or have shown a poor response to oral iron, or, have been diagnosed with chronic kidney disease (CKD) that is non-dialysis dependent. Injectafer isnt a medication that youll take regularly on a schedule. Venofer: Uses, Price, Dosage, Side Effects, Substitute, Buy Online VenAccess is a trademark of Vifor (International) Inc. Switzerland. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Injectafer can cause mild or serious side effects. This treatment course is split into two doses of the drug, which are given at least 7 days apart. This hormone is made by your kidneys. Tell all of your health care providers that you take Venofer. If needed, theyll recommend treatment, including certain medications. Theyll do this by checking certain blood tests. Cancer patients who have anemia and are taking an ESA. For example, some people with anemia have extreme fatigue (lack of energy), which can make it hard for them to exercise. Selected from data included with permission and copyrighted by First Databank, Inc. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. No, you dont need to follow a specific diet plan while youre using Injectafer unless your doctor recommends otherwise. If you notice other effects not listed above, contact your doctor or pharmacist. There are different types of anemia, but IDA is the most common type. Version: 7.01. Hypophosphatemia risk appears to be substantially lower with other IV iron formulations. Theseside effectsmay last as long as they are undercancer treatment. iron sucrose (injection) Uses, Side Effects, Dosage & Interactions taste impairment. Venofer treatment may be repeated if iron deficiency reoccurs. Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Does Daxxify Work Better Than Botox? I Tried The New Neurotoxin. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use. But some people have a delayed allergic reaction to certain drugs. An iron infusion is a way to increase the body's iron levels quickly. For this purpose, Injectafer is approved for use in adults who either: Venofer is also approved to treat IDA. dizziness. With IV infusion, the drug is given as a slow drip into your vein over a period of time. wAd**CgI%"nn{Oa[q{r5 It can be given as a slow injection over 2 to 5 minutes or as an infusion. If you have iron deficiency anemia (IDA), there are certain foods you can eat that may help increase your iron levels. Injectafer begins working as soon as it enters your body. Fortunately, knowing how longside effectslast can help those suffering know what to donext. The next time the doctor prescribesprescription medication, ask aboutcommonside effectsand if they are known to last a short or longtime. With this condition, you also have a low hemoglobin level. Theyll recommend how to manage your condition. <> Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. You may report side effects to FDA at 1-800-FDA-1088. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. Do not start, stop, or change the dose of any drug without checking with your doctor. This medication is given by injection into a vein as directed by your doctor. Orofer S 50 Injection 1 Injection in 1 Packet 147. But if they become more severe or dont go away, talk with your doctor or pharmacist. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Last updated on Feb 20, 2023. In the US - Call your doctor for medical advice about side effects. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. This is because alcohol reduces your bodys absorption of certain nutrients that are necessary to make red blood cells. Other side effects include: Common (may affect up to 1 in 10 users) Temporary taste changes (especially metallic taste) Low blood pressure or high blood pressure. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Also tell them about any vitamins, herbs, and supplements you use. Some drugs may have another patient information leaflet. Canada residents can call a provincial poison control center. Youll receive doses of Injectafer from a healthcare professional at a medical facility. Drug interactions may change how your medications work or increase your risk for serious side effects. Vomiting. Together, you and your doctor can develop a treatment plan thats best for you. Below are examples of these side effects. With anemia, you have a low level of red blood cells (RBCs) in your body. Injectafer and Feraheme have different approved uses, but theyre both used to treat IDA in certain adults. This is not a list of all drugs or health problems that interact with this medicine. Things to remember when you fill your prescription. There are 2 tests that your doctor will likely But for other people, doing so could lead to having too much iron in their body. Drug class: Iron products. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Phosphorus also helps your nerves function properly. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. Knowing how longside effectslast can help with the decision on whether to use a particulardrug. Some products that may interact with this drug include: vitamin products, other iron-containing products. These side effects can range from being mild to severe. Back pain. If this happens to you, your doctor may recommend that you receive another treatment course of Injectafer. The Injectafer dosage your doctor prescribes will depend on your body weight. For instance, there are some experts who believe there are long-lastingside effectsfromCOVIDthat were not aware of just yet. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Venofer. muscle pain. Theseeffects of medicine on thebodycan also lead to medication non-compliance and worsening of themedical conditionthey are meant to treat. This is why family members often have the same issues with drugs as others in theirfamily. For additional information, contact your healthcare provider. Both Injectafer and Feraheme belong to a class of medications known as iron replacement products. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. Examples of thisinclude: Not allside effectslast forever. The information provided is not intended to replace your healthcare provider's medical advice. Tell your doctor if you are taking iron supplements or other iron-based oral medications. Injectafer isnt available in a generic form. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. This website is intended for use by US healthcare professionals only. If you miss an appointment for your Injectafer dose, youll need to call your doctors office. This means you would get two Injectafer doses of 720 mg each. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. How is Venofer (iron sucrose) given? }|54U|O~?|_v;f\o^(W+/-|^)O65_)rd sm }[x[)y.z Wz?9_jV0ub,`g`s?oXOSp/Kgw$b!Vb$;IvBVR9n|\0ln=;/=,mgw@do,[";/8nJL{n}Bb-|^6[~>a_1H'^M:^vv=iM+x|+Y Be ready to tell or show what was taken, how much, and when it happened. Your doctor will go over your Iron Sucrose (Intravenous Route) Precautions - Mayo Clinic The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. Taking a higher dose than needed can often lead to adverse effects. Iron sucrose can also be mixed in a saline solution and given through an IV over a longer time. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. These symptoms can include: While youre taking Injectafer, your doctor will monitor your phosphorus levels if youre at risk for hypophosphatemia. The benefit of treating your condition during pregnancy may outweigh any risks. This way, if you have an allergic reaction to Injectafer, your healthcare professional can treat your reaction. Low iron saturation, or iron deficiency, has various possible causes. I had my first infusion of 1gm 10 days ago. We cancelled my 5th because of the reaction. Iron is an essential nutrient needed to maintain energy levels and keep you healthy. Maintain a well-balanced diet, and follow any dietary guidelines as directed by your doctor. It depends. Clinical trials showed that Injectafer is effective in increasing hemoglobin levels in people with iron deficiency anemia (IDA). If you have diarrhea while youre taking Injectafer, call your doctor. Change in taste. Any long-term side effects/dangers from iron infusions? Infusion times range from less than 20 minutes to up to 4 hours. Venofer (iron sucrose) injection, USP is an intravenous (IV) form of iron, which is a key ingredient for making new red blood cells. You may report side effects to the FDA at 1-800-332-1088. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Those going through thismedical conditionshould speak to theircare teamfor support andguidance. Effectiveness of Injectafer compared with iron thats taken by mouth. In clinical studies, Injectafer was effective in treating IDA in adults who either didnt improve with or had side effects from taking iron by mouth. Remember that it is best to get your vitamins and minerals from food whenever possible. If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. Best food forward: Are algae the future of sustainable nutrition? For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Hes an expert in genetic testing, genetic analysis, andprecision medicine. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. Signs of high or low blood pressure like very bad headache or dizziness, passing out, or change in eyesight. Call your doctor for medical advice about side effects. Pain in your limbs. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Venofer (iron sucrose) is given as an injection into the veins (intravenously or IV) by a trained healthcare provider. Venofer (iron sucrose) dosing, indications, interactions, adverse But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. The drug helps increase your hemoglobin level back to a value thats within the normal range. You may wonder how Injectafer compares with other medications that are prescribed for similar uses. signs of inflammation in the lining of your stomach - pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, fever. A variety of tests can diagnose iron deficiency anemia. Find out what health conditions may be a health risk when taken with Venofer Vial For example: Say you weigh 105 pounds (about 48 kilograms). And this could lead to weight gain, if they increase their food intake. (A generic drug is an exact copy of the active drug in a brand-name medication.) Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. This includes people who: Usually, hypophosphatemia doesnt cause symptoms. monitor along with your hemoglobin and red blood cell count: The Venofer patient brochure provides information and support for CKD patients (2 years and older) with IDA. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. The factors influencing how longside effectslast may not provide the answer most are looking for, but it does explain why some people cant take certain medications because theside effectsareunbearable.